SCHEMBL6679153

SCHEMBL6679153

CC1=NN(C)C(=O)C1=Cc1c(C)nn(C)c1O

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.36
▸ GAA P10253 3/20 0.36
▸ MAPT P10636 9/20 0.35
▸ MEN1 O00255 4/20 0.35
▸ KMT2A Q03164 4/20 0.35
▸ HPGD P15428 2/20 0.33
▸ POLB P06746 1/20 0.33
▸ TDP1 Q9NUW8 1/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.32
▸ NPC1 O15118 1/20 0.31
▸ RAB9A P51151 1/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ MAPK1 P28482 2/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14267880 1.00 ALDH1A1 (0.36) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL6679145 1.00 ALDH1A1 (0.36) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL7866881 0.84 MAPT (0.31) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL7866883 0.84 MAPT (0.31) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL22314252 0.83 ALDH1A1 (0.36) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL6678561 0.83 ALDH1A1 (0.36) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL6682431 0.81 ALDH1A1 (0.35) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL6682436 0.81 ALDH1A1 (0.35) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL14267879 0.75 MAPT (0.35) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL6679326 0.70 ALDH1A1 (0.35) ALDH1A1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1033965-B1 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS WELLA AG (DE) 2004-11-24 — — EP claimed
EP-0980236-B1 COLOURANT AND METHOD FOR PRODUCING TEMPORARY HAIR COLOURS WELLA AG (DE) 2003-04-23 — — EP claimed
US-6361571-B1 USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-26 — — US claimed
EP-1033965-A2 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS Wella Aktiengesellschaft (DE) 2000-09-13 — — EP claimed
WO-1999059529-A2 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 — — WO claimed
US-12569470-B2 Vasodilator and use thereof BIORADICAL RESEARCH INSTITUTE CORP. (JP) 2026-03-10 — — US disclosed
US-20230330066-A1 Vasodilator and Use Thereof BIORADICAL RESEARCH INSTITUTE CORP. (JP) 2023-10-19 — — US disclosed
US-20220110916-A1 Antioxidant and Use Thereof BIORADICAL RESEARCH INSTITUTE CORP. (JP) 2022-04-14 — — US disclosed
US-7955775-B2 Image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2011-06-07 — — US disclosed
US-7955775-B2 Image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2011-06-07 — — US disclosed
US-20070212636-A1 Image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2007-09-13 — — US disclosed
US-20070212636-A1 Image-forming method using heat-sensitive transfer system FUJIFILM CORPORATION (JP) 2007-09-13 — — US disclosed
EP-1033965-B1 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS WELLA AG (DE) 2004-11-24 — — EP disclosed
EP-0980236-B1 COLOURANT AND METHOD FOR PRODUCING TEMPORARY HAIR COLOURS WELLA AG (DE) 2003-04-23 — — EP disclosed
US-6361571-B1 USING TAUTOMERIC NONOXIDATIVE DYES AND POLYMETHINE DYES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-26 — — US disclosed
US-6312478-B1 TWO COMPONENT KIT; ONE COMPONENT IS A COLORANT COMPRISING A MONOMETHINE OR POLYMETHINE DYE; SECOND COMPONENT CONSISTING OF A DECOLORIZING AGENT WELLA AKTIENGESELLSCHAFT (DE) 2001-11-06 — — US disclosed
EP-1033965-A2 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS Wella Aktiengesellschaft (DE) 2000-09-13 — — EP disclosed
EP-0980236-A1 COLOURANT AND METHOD FOR PRODUCING TEMPORARY HAIR COLOURS Wella Aktiengesellschaft (DE) 2000-02-23 — — EP disclosed
WO-1999059529-A2 AGENTS AND METHOD FOR PRODUCING SEMI-PERMANENT COLORATIONS OF KERATIN FIBERS WELLA AKTIENGESELLSCHAFT (DE) 1999-11-25 — — WO disclosed
WO-1999044569-A1 COLOURANT AND METHOD FOR PRODUCING TEMPORARY HAIR COLOURS WELLA AKTIENGESELLSCHAFT (DE) 1999-09-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230330066-A1 Vasodilator and Use Thereof NOX4, NOX1, NOX5 ALDH1A1 466/4885GAA 4371/4885MAPT 4197/4885
US-12569470-B2 Vasodilator and use thereof ROS1, NOX3, ADRB3 ALDH1A1 439/4885GAA 2918/4885MAPT 4759/4885
US-20220110916-A1 Antioxidant and Use Thereof GPX1, GPX4, SOD1 ALDH1A1 137/4885GAA 3447/4885MAPT 4229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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