Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 5/20 | 0.31 |
| ▸ | MAOA | P21397 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28890126 | 0.85 | AKR1C1 (0.46) | AKR1C1KMT2AHTTLMNAHSD11B1 | |
| SCHEMBL6680771 | 0.81 | AKR1C1 (0.37) | AKR1C1MEN1KMT2AHTTLMNA | |
| SCHEMBL6681685 | 0.80 | AKR1C1 (0.34) | AKR1C1MEN1KMT2AHTTLMNA | |
| SCHEMBL5614157 | 0.77 | HCAR3 (0.36) | AKR1C1MEN1KMT2ALMNACYP1A2 | |
| SCHEMBL6677871 | 0.73 | AKR1C1 (0.34) | AKR1C1MEN1KMT2AHTTCYP1A2 | |
| SCHEMBL6677071 | 0.73 | SMN1; SMN2 (0.36) | MEN1KMT2ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6679022 | 0.73 | HCAR3 (0.33) | AKR1C1MEN1KMT2AHTTLMNA | |
| SCHEMBL6679652 | 0.72 | CES2 (0.36) | AKR1C1MEN1KMT2AHTTNPSR1 | |
| SCHEMBL29031869 | 0.71 | ALOX15 (0.44) | MEN1KMT2ALMNACYP2C9CYP2C19 | |
| SCHEMBL6677414 | 0.70 | KMT2A (0.40) | AKR1C1MEN1KMT2AHTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |