Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6677414 | 0.81 | KMT2A (0.40) | MEN1KMT2AHTTTSHRALDH1A1 | |
| SCHEMBL28890126 | 0.78 | AKR1C1 (0.46) | KMT2AHTTTSHRALDH1A1AKR1C1 | |
| SCHEMBL6680771 | 0.74 | AKR1C1 (0.37) | MEN1KMT2AHTTAKR1C1CCR2 | |
| SCHEMBL6639935 | 0.73 | OPRM1 (0.39) | MEN1KMT2AHTTAKR1C1HCAR3 | |
| SCHEMBL6679652 | 0.73 | CES2 (0.36) | MEN1KMT2AHTTTSHRALDH1A1 | |
| SCHEMBL6677871 | 0.70 | AKR1C1 (0.34) | MEN1KMT2AHTTAKR1C1CCR2 | |
| SCHEMBL6678308 | 0.70 | AKR1C1 (0.34) | MEN1KMT2AHTTTSHRALDH1A1 | |
| SCHEMBL6677394 | 0.67 | AKR1C1 (0.37) | MEN1KMT2AHTTAKR1C1SMN1; SMN2 | |
| SCHEMBL5614157 | 0.67 | HCAR3 (0.36) | MEN1KMT2ATSHRAKR1C1HCAR3 | |
| SCHEMBL6677071 | 0.67 | SMN1; SMN2 (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |