Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | WRN | Q14191 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | DNTT | P04053 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679387 | 0.86 | NLRP3 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL6676582 | 0.83 | PPARG (0.41) | PPARGPPARDPPARADNTTNFKB1 | |
| SCHEMBL6676379 | 0.81 | PPARG (0.48) | PPARGPPARDPPARADNTT | |
| SCHEMBL6675746 | 0.81 | PPARG (0.48) | PPARGPPARDPPARADNTT | |
| SCHEMBL6676521 | 0.77 | TRPA1 (0.35) | ALDH1A1HPGDHIF1APPARGPPARD | |
| SCHEMBL6676518 | 0.77 | TRPA1 (0.35) | ALDH1A1HPGDHIF1APPARGPPARD | |
| SCHEMBL6678682 | 0.76 | POLB (0.40) | CYP2C19PPARGPPARDPPARA | |
| SCHEMBL6676309 | 0.71 | MIF (0.33) | — | |
| SCHEMBL18892599 | 0.69 | HIF1A (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM | |
| SCHEMBL2242442 | 0.67 | ALDH1A1 (0.38) | ALDH1A1CYP1A2HPGDCYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | claimed |
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | disclosed |