Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | DNTT | P04053 | 1/20 | 0.33 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | WRN | Q14191 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | BCL9 | O00512 | 1/20 | 0.30 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676582 | 0.90 | PPARG (0.41) | NLRP3PPARGPPARDPPARADNTT | |
| SCHEMBL6675203 | 0.89 | PPARG (0.46) | NLRP3PPARGPPARDPPARADNTT | |
| SCHEMBL6680397 | 0.88 | PPARG (0.48) | NLRP3PPARGPPARDPPARADNTT | |
| SCHEMBL6675746 | 0.88 | PPARG (0.48) | NLRP3PPARGPPARDPPARADNTT | |
| SCHEMBL6676379 | 0.88 | PPARG (0.48) | NLRP3PPARGPPARDPPARADNTT | |
| SCHEMBL6680654 | 0.86 | ALDH1A1 (0.41) | PPARGPPARDPPARAALDH1A1DNTT | |
| SCHEMBL6676518 | 0.77 | TRPA1 (0.35) | PPARGPPARDPPARAALDH1A1DNTT | |
| SCHEMBL6678682 | 0.73 | POLB (0.40) | NLRP3PPARGPPARDPPARACYP2C19 | |
| SCHEMBL6674835 | 0.72 | TAS1R3 (0.33) | PPARGPPARDPPARADNTT | |
| Methyl Alcohol SCHEMBL6679682 | 0.72 | POLB (0.39) | CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | claimed |
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | disclosed |