Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664310 | 0.92 | ALDH1A1 (0.53) | KMT2AMEN1NPSR1TSHRTP53 | |
| SCHEMBL6664439 | 0.85 | CHRM3 (0.56) | KMT2ATP53CHRM3 | |
| SCHEMBL6665392 | 0.84 | ALDH1A1 (0.51) | KMT2AMEN1NPSR1TP53GAA | |
| SCHEMBL6663459 | 0.80 | CHRM3 (0.58) | KMT2ACHRM3 | |
| SCHEMBL6665368 | 0.79 | NPSR1 (0.52) | KMT2AMEN1NPSR1TSHRTP53 | |
| SCHEMBL6681189 | 0.79 | ALDH1A1 (0.61) | KMT2AMEN1NPSR1TP53HTT | |
| SCHEMBL21052224 | 0.79 | CHRM3 (0.75) | CHRM3 | |
| SCHEMBL6669041 | 0.79 | ALDH1A1 (0.48) | KMT2ANPSR1TSHRTP53LMNA | |
| SCHEMBL6664922 | 0.79 | NPSR1 (0.48) | KMT2ANPSR1TSHRTP53KDM4E | |
| SCHEMBL6663170 | 0.75 | CHRM3 (0.67) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014425-A1 | ACTIVATORS OF SMALL CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNELS AND USE THEREOF | GLAXO GROUP LIMITED (GB) | 2004-02-19 | — | — | WO | disclosed |