Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | DNTT | P04053 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 6/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6675203 | 0.95 | PPARG (0.46) | PPARGPPARDPPARADNTTNAAA | |
| SCHEMBL6680397 | 0.94 | PPARG (0.48) | PPARGPPARDPPARADNTTNAAA | |
| SCHEMBL6676379 | 0.94 | PPARG (0.48) | PPARGPPARDPPARADNTTNAAA | |
| SCHEMBL6675746 | 0.94 | PPARG (0.48) | PPARGPPARDPPARADNTTNAAA | |
| SCHEMBL6679387 | 0.90 | NLRP3 (0.38) | PPARGPPARDPPARADNTTNLRP3 | |
| SCHEMBL6680654 | 0.83 | ALDH1A1 (0.41) | PPARGPPARDPPARADNTTNFKB1 | |
| SCHEMBL6676518 | 0.80 | TRPA1 (0.35) | PPARGPPARDPPARAMIFDNTT | |
| SCHEMBL2238652 | 0.71 | LMNA (0.47) | NAAAPRKCA | |
| SCHEMBL6678682 | 0.71 | POLB (0.40) | PPARGPPARDPPARANLRP3 | |
| SCHEMBL2240258 | 0.70 | NAAA (0.41) | NAAAPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | claimed |
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | disclosed |