Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10138510 | 0.86 | ALDH1A1 (0.50) | ALDH1A1GAAMAPTTSHRHPGD | |
| SCHEMBL21164288 | 0.85 | MGLL (0.38) | MGLLALDH1A1GRM5KDM1AKCNH2 | |
| SCHEMBL19272949 | 0.84 | ALDH1A1 (0.36) | ALDH1A1GAATSHRHPGDSMN1; SMN2 | |
| SCHEMBL15958517 | 0.82 | ALDH1A1 (0.42) | MGLLALDH1A1GRM5KDM1AHPGDS | |
| SCHEMBL10472613 | 0.82 | MGLL (0.36) | MGLLALDH1A1TSHRHPGD | |
| SCHEMBL16961695 | 0.79 | ALDH1A1 (0.39) | MGLLALDH1A1GRM5KDM1AHPGDS | |
| SCHEMBL202404 | 0.78 | ALDH1A1 (0.61) | ALDH1A1GRM5KDM1AHPGDS | |
| SCHEMBL6682154 | 0.77 | ALDH1A1 (0.41) | MGLLALDH1A1GRM5KDM1AHPGDS | |
| SCHEMBL3628529 | 0.77 | EPAS1 (0.41) | MGLLALDH1A1GRM5KDM1AHPGDS | |
| SCHEMBL158444 | 0.76 | MGLL (0.36) | MGLLALDH1A1GRM5KDM1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10336748-B2 | Methyoxy-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof | PFIZER INC. (US) | 2019-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10336748-B2 | Methyoxy-substituted pyrrolopyridine modulators of RORC2 and methods of use thereof | RORC, RORB, RORA | MGLL 4128/4885ALDH1A1 484/4885GAA 1994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.