Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.30 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.30 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL558506 | 0.76 | DRD2 (0.44) | — | |
| SCHEMBL4723413 | 0.73 | ALDH1A1 (0.46) | — | |
| SCHEMBL16719635 | 0.68 | MAOA (0.39) | — | |
| SCHEMBL17710270 | 0.67 | MGLL (0.42) | NR1H2SCN9A | |
| SCHEMBL28013628 | 0.67 | NPC1 (0.50) | HTR1ASLC6A2SLC6A4SLC6A3CYP19A1 | |
| SCHEMBL2750741 | 0.64 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL15015154 | 0.63 | MAPK14 (0.55) | HTR1ASLC6A2SLC6A4MAPK14 | |
| SCHEMBL10753674 | 0.63 | ALDH1A1 (0.39) | PIM1PIM2CYP19A1MAPK14 | |
| SCHEMBL15201678 | 0.63 | LCK (0.40) | HTR1ASLC6A2SLC6A4SLC6A3PIM1 | |
| SCHEMBL7408341 | 0.63 | HTT (0.72) | HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004030637-A2 | TREATMENT OF OBESITY AND OTHER DISORDERS ASSOCIATED WITH EXCESSIVE FOOD INTAKE | MERCK & CO., INC. (US) | 2004-04-15 | — | — | WO | claimed |