Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2125627 | 0.88 | ALDH1A1 (0.40) | HTR7SLC6A3SLC6A2SLC6A4AOC3 | |
| SCHEMBL28771612 | 0.83 | BDKRB2 (0.47) | LMNAMEN1TP53KMT2ASMN1; SMN2 | |
| SCHEMBL7640359 | 0.82 | HRH3 (0.45) | SMN1; SMN2 | |
| SCHEMBL5795845 | 0.82 | CYP1A2 (0.38) | SLC6A3SLC6A2SLC6A4LMNATP53 | |
| SCHEMBL28771738 | 0.80 | BDKRB2 (0.40) | SLC6A3SLC6A2CHRM1SLC6A4LMNA | |
| SCHEMBL7217195 | 0.80 | SLC6A2 (0.44) | SLC6A3SLC6A2SLC6A4AOC3LMNA | |
| SCHEMBL4059571 | 0.80 | ESR1 (0.52) | SLC6A3SLC6A2DRD3CHRM1SLC6A4 | |
| SCHEMBL11447090 | 0.79 | HTR7 (0.36) | HTR7SLC6A3SLC6A2DRD2DRD4 | |
| SCHEMBL6391223 | 0.79 | PDE2A (0.41) | SLC6A4LMNAMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL1920593 | 0.79 | POLB (0.45) | AOC3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101948368-B | Diphenylalkyl halide or diphenyl carboxylic acid and synthesis method thereof | SHANGHAI INST ORGANIC CHEM | 2013-09-25 | — | — | CN | disclosed |
| CN-101948368-A | Diphenylalkyl halide or diphenyl carboxylic acid and synthesis method thereof | SHANGHAI INST ORGANIC CHEM | 2011-01-19 | — | — | CN | disclosed |
| WO-2004111056-A2 | COMPOUND LIBRARIES OF SPIRO-BENZODIOXINE-PIPERIDINES | BIOFOCUS PLC (GB) | 2004-12-23 | — | — | WO | disclosed |
| WO-2004035568-A1 | BENZOFURAN DERIVATIVES, FORMULATIONS AND USES THEREOF | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2004-04-29 | — | — | WO | disclosed |