SCHEMBL6684539

SCHEMBL6684539

C=C(C)c1ccc(C(C)O[SiH3])cc1

nearest known ligand 0.41

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10603240 0.76 ESR1 (0.50) HTT
SCHEMBL3481795 0.76 CHRNA7 (0.41) CA1CA2CA7CA9
SCHEMBL717192 0.76 HTT (0.52) HTT
SCHEMBL7550553 0.74 NOS3 (0.45) HTT
SCHEMBL8441986 0.74 HTT (0.35) HTT
SCHEMBL20433702 0.72 ADRB2 (0.48) HTT
SCHEMBL56361 0.72 MAPT (0.40) HTT
SCHEMBL10514359 0.72
SCHEMBL24146431 0.72 HPGD (0.33) HTT
SCHEMBL21093726 0.71 HTT (0.47) HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0823450-B1 COMPOSITE AND MOLDINGS PRODUCED THEREFROM MITSUBISHI RAYON CO (JP) 2004-11-24 EP disclosed
US-5939471-A COLLOIDAL SILICA DISPERSED IN RESIN MITSUBISHI RAYON CO., LTD. (JP) 1999-08-17 US disclosed
EP-0823450-A1 COMPOSITE AND MOLDINGS PRODUCED THEREFROM MITSUBISHI RAYON CO., LTD. (JP) 1998-02-11 EP disclosed