SCHEMBL8441986

SCHEMBL8441986

[CH2]C(C)c1ccc(C(=C)C)cc1

nearest known ligand 0.48

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.35
ESR1 P03372 1/20 0.32
PDCD1 Q15116 1/20 0.32
ESR2 Q92731 1/20 0.32
CD274 Q9NZQ7 1/20 0.32
CYP2C9 P11712 1/20 0.31
HDAC1 Q13547 1/20 0.31
HDAC8 Q9BY41 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
ACHE P22303 1/20 0.31
ALOX5 P09917 1/20 0.31
USP5 P45974 1/20 0.31
CHRNA7 P36544 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL717192 0.83 HTT (0.52) HTTCYP2C9USP5
SCHEMBL10603240 0.83 ESR1 (0.50) HTTESR1PDCD1ESR2CD274
SCHEMBL7550553 0.81 NOS3 (0.45) HTTESR1PDCD1ESR2CD274
SCHEMBL20433702 0.79 ADRB2 (0.48) HTT
SCHEMBL56361 0.79 MAPT (0.40) HTTESR1ESR2
SCHEMBL9539624 0.79 ESR1 (0.38) HTTESR1PDCD1ESR2CD274
SCHEMBL24146431 0.78 HPGD (0.33) HTTESR1CYP2C9
SCHEMBL21093726 0.77 HTT (0.47) HTTCYP2C9USP5
SCHEMBL28149927 0.77 ADRA2C (0.36) HTTCYP2C9HDAC1HDAC8HDAC6
SCHEMBL7596929 0.76 MAPT (0.38) HTTESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013069815-A1 NOVEL COMPOUND HAVING BISAZO DYE SKELETON, PIGMENT COMPOSITION CONTAINING THE SAME, PIGMENT DISPERSION, INK, AND COLOR FILTER RESIST COMPOSITION CANON KABUSHIKI KAISHA (JP) 2013-05-16 WO disclosed
US-5866707-A Process for preparing organosilicon compounds having Si-bonded hydrogen atoms WACKER-CHEMIE GMBH (DE) 1999-02-02 US disclosed