Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.35 |
| ▸ | PTPRZ1 | P23471 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | GIPR | P48546 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685923 | 0.85 | RAB9A (0.38) | SMN1; SMN2NPC1RAB9APOLB | |
| SCHEMBL6685716 | 0.84 | KDM4E (0.47) | ALDH1A1POLBTDP1KDM4E | |
| SCHEMBL6687814 | 0.81 | EPHX1 (0.40) | NPC1RAB9ACYP2D6 | |
| SCHEMBL6693570 | 0.81 | CA2 (0.44) | ALDH1A1RAB9APOLBMAPK1RECQL | |
| SCHEMBL5409955 | 0.81 | EPHX2 (0.47) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL6690542 | 0.80 | RORC (0.41) | ALDH1A1NPSR1 | |
| SCHEMBL6693564 | 0.80 | CDK1 (0.37) | — | |
| SCHEMBL5404160 | 0.80 | EPHX2 (0.46) | ALDH1A1NPC1RAB9APOLBMAPT | |
| SCHEMBL6687352 | 0.80 | MAPT (0.45) | ALDH1A1SMN1; SMN2POLBLMNAMAPT | |
| SCHEMBL6693494 | 0.78 | SLC6A9 (0.37) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |