⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL43673 | 0.88 | PSMB8 (0.33) | — | |
| SCHEMBL109446 | 0.84 | TRPA1 (0.33) | — | |
| SCHEMBL15991602 | 0.75 | TRPA1 (0.35) | — | |
| Succinimide SCHEMBL9417543 | 0.75 | CRBN (0.38) | — | |
| SCHEMBL950852 | 0.73 | — | — | |
| SCHEMBL2608502 | 0.73 | LMNA (0.34) | — | |
| SCHEMBL3542603 | 0.73 | KMT2A (0.35) | — | |
| SCHEMBL11125521 | 0.73 | LMNA (0.34) | — | |
| SCHEMBL668589 | 0.73 | — | — | |
| SCHEMBL28945733 | 0.72 | MGLL (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8618266-B2 | Hasylated polypeptides | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2013-12-31 | — | — | US | disclosed |
| EP-1681303-B1 | HASylated polypeptides, especially HASylated erythropoietin | FRESENIUS KABI DE GMBH (DE) | 2013-09-04 | — | — | EP | disclosed |
| US-20120046240-A9 | Method of Producing Hydroxyalkyl Starch Derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2012-02-23 | — | — | US | disclosed |
| EP-2316850-A2 | HASylated polypeptides, especially HASylated erythropoietin | Fresenius Kabi Deutschland GmbH (DE) | 2011-05-04 | — | — | EP | disclosed |
| EP-2272865-A2 | Method of producing hydroxyalkyl starch derivatives | Fresenius Kabi Deutschland GmbH (DE) | 2011-01-12 | — | — | EP | disclosed |
| US-20100317609-A1 | Method of Producing Hydroxyalkyl Starch Derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2010-12-16 | — | — | US | disclosed |
| EP-2017287-A2 | Method of producing hydroxyalkyl starch derivatives | Fresenius Kabi Deutschland GmbH (DE) | 2009-01-21 | — | — | EP | disclosed |
| EP-1398327-B1 | Method of producing hydroxyalkyl starch derivatives | FRESENIUS KABI DE GMBH (DE) | 2008-08-27 | — | — | EP | disclosed |
| EP-1681303-A1 | HASylated polypeptides, especially HASylated erythropoietin | Fresenius Kabi Deutschland GmbH (DE) | 2006-07-19 | — | — | EP | disclosed |
| EP-1398322-B1 | HASylated polypeptides, especially HASylated erythropoietin | FRESENIUS KABI DE GMBH (DE) | 2006-04-19 | — | — | EP | disclosed |
| US-20060019877-A1 | Hasylated polypeptides | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2006-01-26 | — | — | US | disclosed |
| US-20050238723-A1 | Method of producing hydroxyalkyl starch derivatives | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2005-10-27 | — | — | US | disclosed |
| WO-2004024776-A1 | METHOD OF PRODUCING HYDROXYALKYL STARCH DERIVATIVES | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2004-03-25 | — | — | WO | disclosed |
| WO-2004024761-A1 | HASYLATED POLYPEPTIDES, ESPECIALLY HASYLATED ERYTHROPOIETIN | FRESENIUS KABI DEUTSCHLAND GMBH (DE) | 2004-03-25 | — | — | WO | disclosed |
| EP-1400533-A1 | HASylated polypeptides, especially HASylated erythropoietin | Fresenius Kabi Deutschland GmbH (DE) | 2004-03-24 | — | — | EP | disclosed |
| EP-1398322-A1 | HASylated polypeptides, especially HASylated erythropoietin | Fresenius Kabi Deutschland GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |
| EP-1398327-A1 | Method of producing hydroxyalkyl starch derivatives | Fresenius Kabi Deutschland GmbH (DE) | 2004-03-17 | — | — | EP | disclosed |