SCHEMBL66860

SCHEMBL66860

N=C1NC(=N)c2ccccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.43
S100A4 P26447 2/20 0.38
CASP3 P42574 2/20 0.36
CASP7 P55210 2/20 0.36
CASP6 P55212 2/20 0.36
CASP8 Q14790 2/20 0.36
CASP2 P42575 1/20 0.36
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
CDC25B P30305 3/20 0.35
MAOA P21397 3/20 0.35
MAOB P27338 2/20 0.35
PDGFRA P16234 1/20 0.35
FER P16591 1/20 0.35
LTK P29376 1/20 0.35
CDK8 P49336 1/20 0.35
ACVR1 Q04771 1/20 0.35
LRRK2 Q5S007 1/20 0.35
DYRK1B Q9Y463 1/20 0.35
ALDH1A1 P00352 6/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL18663465 0.97 GSK3B (0.41) GSK3BS100A4CASP3CASP7CASP6
Oxalic Acid SCHEMBL30766245 0.84 THRB (0.40) GSK3BS100A4CASP3CASP7CASP6
Acetic Acid SCHEMBL7830102 0.83 THRB (0.39) GSK3BMEN1KMT2AALDH1A1MAPK1
SCHEMBL160837 0.81 GSK3B (0.67) GSK3BS100A4CASP3CASP7CASP6
SCHEMBL18072702 0.81 GSK3B (0.35) GSK3BS100A4CASP3CASP7CASP6
SCHEMBL29497778 0.81 GSK3B (0.67) GSK3BS100A4CASP3CASP7CASP6
Nitric Acid SCHEMBL10744158 0.81 S100A4 (0.37) GSK3BS100A4CASP6LRRK2ALDH1A1
Benzoic Acid SCHEMBL7827449 0.79 TSHR (0.58) ALDH1A1TSHRCA1CA2CA9
Phthalic Acid SCHEMBL18663463 0.79 ALDH1A1 (0.58) CDC25BALDH1A1SMN1; SMN2L3MBTL1POLB
Succinic Acid SCHEMBL7829045 0.79 APEX1 (0.48) MEN1KMT2AALDH1A1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2819 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260022215-A1 PROCESSABLE POLYIMIDE-PHTHALONITRILE APPLICATION FORMS AND METHODS THEREOF THE BOEING COMPANY (US) 2026-01-22 US claimed
EP-4681825-A1 PROCESSABLE POLYIMIDE-PHTHALONITRILE APPLICATION FORMS AND METHODS THEREOF The Boeing Company (US) 2026-01-21 EP claimed
US-12528789-B2 Isoindoline derivatives SUN CHEMICAL B.V. (NL) 2026-01-20 US claimed
CN-119529341-A Moisture-heat-resistant polylactic acid transparent film and preparation method thereof 广东省国科海纳新材料科技有限公司 2025-02-28 CN claimed
EP-3787400-B1 A DEVICE TO ATTRACT AND INDUCE BLOOD-FEEDING BITING FLIES TO LAND ON IT, AND METHODS RELATED TO THIS DEVICE GUERIN PATRICK (CH) 2024-10-16 EP claimed
CN-118562313-A Preparation method and continuous preparation system of isoindoline pigment 宇虹颜料股份有限公司 2024-08-30 CN claimed
US-20240150506-A1 CURING AGENTS FOR FLUOROELASTOMERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-05-09 US claimed
CN-114466843-B Isoindoline derivatives 巴斯夫色彩与效果有限公司 2024-04-05 CN claimed
CN-114573998-B Pigment yellow 139 synthesis process 山东世纪连泓新材料有限公司 2024-03-05 CN claimed
CN-117529520-A Fluoroelastomer compositions containing curative 杜邦特种产品美国有限公司 2024-02-06 CN claimed
EP-0088594-B1 NOVEL ISOINDOLINE CATIONIC DYES MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-05-06 EP claimed
US-4645539-A WEATHERFASTNESS, CONDENSATION WITH BARBITURIC ACID BASF AKTIENGESELLSCHAFT (DE) 1987-02-24 US claimed
EP-0185618-A2 Isoindolines, process for their manufacture and their use CIBA-GEIGY AG (CH) 1986-06-25 EP claimed
US-4521793-A Coloring method and color-forming material ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1985-06-04 US claimed
EP-0101741-A1 COLORING METHOD AND COLOR-FORMING MATERIAL Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1984-03-07 EP claimed
EP-0018589-B1 PROCESS FOR THE PREPARATION OF INSOLUBLE METAL COMPLEX DYES BASF Aktiengesellschaft (DE) 1983-06-15 EP claimed
US-4321390-A Preparation of insoluble metal complex colorants BASF AKTIENGESELLSCHAFT (DE) 1982-03-23 US claimed
US-4311527-A WITH PYRAZOLONE GROUPS; COLORED POLYMERS, COATINGS BASF AKTIENGESELLSCHAFT (DE) 1982-01-19 US claimed
EP-0029007-A1 Isoindoline pigments, process for their preparation and their use CIBA-GEIGY AG (CH) 1981-05-20 EP claimed
EP-0018589-A2 Process for the preparation of insoluble metal complex dyes BASF Aktiengesellschaft (DE) 1980-11-12 EP claimed