Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411231 | 0.90 | TSHR (0.53) | TSHRALDH1A1GAAMMP8F2 | |
| SCHEMBL9911026 | 0.88 | TSHR (0.51) | TSHRALDH1A1GAAMMP8F2 | |
| SCHEMBL1244623 | 0.88 | TSHR (0.55) | TSHRALDH1A1GAAMMP8F2 | |
| SCHEMBL11740036 | 0.84 | LMNA (0.53) | TSHRALDH1A1GAAMMP8F2 | |
| SCHEMBL7178642 | 0.82 | ALDH1A1 (0.55) | TSHRALDH1A1MMP8F2MEN1 | |
| SCHEMBL9911027 | 0.81 | ALDH1A1 (0.46) | TSHRALDH1A1GAAMMP8F2 | |
| SCHEMBL232194 | 0.81 | F2 (0.59) | TSHRALDH1A1MMP8F2MEN1 | |
| SCHEMBL28719688 | 0.80 | TSHR (0.45) | TSHRALDH1A1GAAMMP8F2 | |
| SCHEMBL3670529 | 0.80 | L3MBTL1 (0.48) | TSHRALDH1A1GAAMMP8MEN1 | |
| SCHEMBL23027267 | 0.79 | LTB4R (0.54) | TSHRALDH1A1MMP8F2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004070049-A1 | THE ENZYMATIC METHOD OF MAKING ETHYL 3-HYDROXY-3-PHENYLPROPIONATE AND THEIR ESTERS | ENZYTECH, LTD. (KR) | 2004-08-19 | — | — | WO | disclosed |