Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 4/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-Aminoguanine SCHEMBL21760 | 0.83 | KDM4E (0.60) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL9115 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL159447 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL843931 | 0.76 | LMNA (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL158423 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL42761 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL844206 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL2206472 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL160586 | 0.76 | ALDH1A1 (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL912731 | 0.74 | KDM4E (0.51) | KDM4EGLAALDH1A1LMNAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004019885-A2 | FAST DISSOLVING FILM DELIVERY OF NUCLEOTIDES THAT INHIBIT THE UNPLEASANT TASTE OF BITTER TASTING MEDICATIONS | LINGUAGEN CORP. (US) | 2004-03-11 | — | — | WO | disclosed |