SCHEMBL9115

SCHEMBL9115

Nc1nc2[nH]c(Br)nc2c(=O)[nH]1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 1/20 0.53
LMNA P02545 1/20 0.53
GLA P06280 1/20 0.53
PMP22 Q01453 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAPT P10636 1/20 0.46
MITF O75030 1/20 0.44
TP53 P04637 1/20 0.44
THRB P10828 1/20 0.44
ALOX15 P16050 1/20 0.44
HBB P68871 1/20 0.44
HIF1A Q16665 1/20 0.44
DYRK1A Q13627 1/20 0.42
PNP P00491 4/20 0.41
XDH P47989 1/20 0.39
CDK1 P06493 1/20 0.37
CDK4 P11802 1/20 0.37
CDK2 P24941 1/20 0.37
TYMS P04818 4/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
8-Aminoguanine SCHEMBL21760 0.83 KDM4E (0.60) KDM4EALDH1A1LMNAGLAPMP22
Niacinamide SCHEMBL6559644 0.76 F7 (0.51) KDM4EALDH1A1LMNAGLAPMP22
SCHEMBL844206 0.76 KDM4E (0.53) KDM4EALDH1A1LMNAGLAPMP22
SCHEMBL2206472 0.76 KDM4E (0.53) KDM4EALDH1A1LMNAGLAPMP22
SCHEMBL160586 0.76 ALDH1A1 (0.53) KDM4EALDH1A1LMNAGLAPMP22
SCHEMBL42761 0.76 KDM4E (0.53) KDM4EALDH1A1LMNAGLAPMP22
SCHEMBL6686385 0.76 KDM4E (0.53) KDM4EALDH1A1LMNAGLAPMP22
SCHEMBL158423 0.76 KDM4E (0.53) KDM4EALDH1A1LMNAGLAPMP22
SCHEMBL159447 0.76 KDM4E (0.53) KDM4EALDH1A1LMNAGLAPMP22
SCHEMBL843931 0.76 LMNA (0.53) KDM4EALDH1A1LMNAGLAPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2537 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026106497-A2 FUNCTIONALIZED CIRCULAR RNA AND METHODS AND INTERMEDIATES FOR THEIR PRODUCTION SIEĆ BADAWCZA ŁUKASIEWICZ – PORT POLSKI OSRODEK ROZWOJU TECHNOLOGII (PL) 2026-05-21 WO claimed
EP-4638717-A2 ENGINEERED RNA LIGASE VARIANTS Codexis, Inc. (US) 2025-10-29 EP claimed
US-20250295658-A1 ANTIPARASITIC AGENTS AND METHODS WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH 2025-09-25 US claimed
EP-4619524-A1 METHODS AND COMPOSITIONS FOR PREVENTING, TREATING, OR REVERSING CARDIAC DIASTOLIC DYSFUNCTION Genkardia Inc. (US) 2025-09-24 EP claimed
US-20250257360-A1 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER UNIV OKLAHOMA (US) 2025-08-14 US claimed
CN-113151261-B Antisense oligonucleotides as inhibitors of TGF-R signaling 神经视觉医药有限公司 2025-06-17 CN claimed
WO-2025111510-A1 ENGINEERED RNA LIGASES CODEXIS, INC. (US) 2025-05-30 WO claimed
EP-4504945-A2 OLIGONUCLEOTIDE INTERFERENCE TREATMENTS OF PROSTATE CANCER The Board of Regents of the University of Oklahoma (US) 2025-02-12 EP claimed
CN-118931997-A Method for synthesizing adenosine and/or uridine by three-enzyme cascade catalysis 上海飞腾医药科技有限公司 2024-11-12 CN claimed
US-20240294924-A1 ANTISENSE-OLIGONUCLEOTIDES FOR PREVENTION OF KIDNEY DYSFUNCTION PROMOTED BY ENDOTHELIAL DYSFUNCTION BY EPHRIN-B2 SUPPRESSION MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2024-09-05 US claimed
WO-1996016972-A1 PURINE NUCLEOSIDE MODIFICATIONS BY PALLADIUM CATALYZED METHODS NEXSTAR PHARMACEUTICALS, INC. (US) 1996-06-06 WO claimed
US-5438130-A Fucosylated guanosine disulfates as excitatory amino acid antagonists CAMBRIDGE NEUROSCIENCE, INC. (US) 1995-08-01 US claimed
WO-1995008003-A1 SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT: PHOTOSELECTION OF NUCLEIC ACID LIGANDS AND SOLUTION SELEX UNIVERSITY RESEARCH CORPORATION (US) 1995-03-23 WO claimed
US-5386030-A Chemical intermediates INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCE OF THE CZECH REPUBLIC (CZ) 1995-01-31 US claimed
EP-0630381-A4 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. 1995-01-04 EP claimed
EP-0630381-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES. ACAD OF SCIENCE CZECH REPUBLIC (CS) 1994-12-28 EP claimed
WO-1994015622-A1 NUCLEOSIDE DERIVATIVES AND THEIR USE AS EXCITATORY AMINO ACID ANTAGONISTS CAMBRIDGE NEUROSCIENCE (US) 1994-07-21 WO claimed
US-5208221-A Nucleotides and intermediates for herpes virus or leukemia virus BRISTOL-MYERS SQUIBB COMPANY (US) 1993-05-04 US claimed
WO-1993007157-A1 ANTIVIRAL ACYCLIC PHOSPHONOMETHOXYALKYL SUBSTITUTED, ALKENYL AND ALKYNYL PURINE AND PYRIMIDINE DERIVATIVES INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OFTHE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CZ) 1993-04-15 WO claimed
EP-0269947-A1 Antiviral phosphonomethoxyalkylene purine and pyrimidine derivatives INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) 1988-06-08 EP claimed