Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | PNP | P00491 | 4/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | TYMS | P04818 | 1/20 | 0.36 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 8-Aminoguanine SCHEMBL21760 | 0.83 | KDM4E (0.60) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL160586 | 0.76 | ALDH1A1 (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL159447 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL843931 | 0.76 | LMNA (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL844206 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL42761 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL158423 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL9115 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL6686385 | 0.76 | KDM4E (0.53) | KDM4EGLAALDH1A1LMNAPMP22 | |
| SCHEMBL912731 | 0.74 | KDM4E (0.51) | KDM4EGLAALDH1A1LMNAPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150157655-A1 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SENA RESEARCH, INC. (US) | 2015-06-11 | — | — | US | claimed |
| CN-104540843-A | Selenium containing nucleosides as nutritional supplements | SENA RES INC | 2015-04-22 | — | — | CN | claimed |
| WO-2014003950-A2 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SENA RESEARCH, INC. (US) | 2014-01-03 | — | — | WO | claimed |
| US-7982030-B2 | Synthesis of selenium-derivatized nucleosides, nucleotides, phosphoramidites, triphosphates and nucleic acids | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2011-07-19 | — | — | US | claimed |
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-06-03 | — | — | US | claimed |
| US-4617189-A | Use of selenium-containing compounds for negating the toxic effects of platinum compounds used in chemotherapy, and a novel selenium-containing platinum compound and use thereof as an anti-cancer medicine | STOCKEL RICHARD F (US) | 1986-10-14 | — | — | US | claimed |
| US-20150157655-A1 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SENA RESEARCH, INC. (US) | 2015-06-11 | — | — | US | disclosed |
| CN-104540843-A | Selenium containing nucleosides as nutritional supplements | SENA RES INC | 2015-04-22 | — | — | CN | disclosed |
| WO-2014003950-A2 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SENA RESEARCH, INC. (US) | 2014-01-03 | — | — | WO | disclosed |
| US-4617189-A | Use of selenium-containing compounds for negating the toxic effects of platinum compounds used in chemotherapy, and a novel selenium-containing platinum compound and use thereof as an anti-cancer medicine | STOCKEL RICHARD F (US) | 1986-10-14 | — | — | US | disclosed |
| US-4536571-A | SEFL-DETOXIFYING ANTICARCINOGENIC AGENT | STOCKEL RICHARD F (US) | 1985-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137573-A1 | SYNTHESIS OF SELENIUM-DERIVATIZED NUCLEOSIDES, NUCLEOTIDES, PHOSPHORAMIDITES, TRIPHOSPHATES AND NUCLEIC ACIDS | SELENOI, RNGTT, NT5C3B | KDM4E 4246/4885GLA 3794/4885ALDH1A1 3517/4885 |
| US-20150157655-A1 | SELENIUM CONTAINING NUCLEOSIDES AS NUTRITIONAL SUPPLEMENTS | SLC28A1, SLC28A2, SLC5A6 | KDM4E 4212/4885GLA 2252/4885ALDH1A1 1754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.