Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7278573 | 0.84 | NAAA (0.50) | NAAAHCAR2EPHX1TSHR | |
| SCHEMBL28990192 | 0.84 | ACHE (0.38) | ACHETSHR | |
| SCHEMBL8010937 | 0.82 | ACHE (0.40) | ACHEGPR84FFAR1FFAR4TSHR | |
| SCHEMBL11876606 | 0.82 | ALDH1A1 (0.52) | ACHENAAAHCAR2EPHX1TSHR | |
| Ethylmalonate SCHEMBL31396325 | 0.81 | GPR84 (0.46) | GPR84FFAR1FFAR4TSHR | |
| SCHEMBL14739496 | 0.80 | ACHE (0.37) | ACHECYP4F2CYP4A11GPR84FFAR1 | |
| Ammonia Solution, Strong SCHEMBL28672307 | 0.80 | ALDH1A1 (0.50) | ACHENAAAHCAR2EPHX1TSHR | |
| Ethylmalonate SCHEMBL30720824 | 0.79 | SMN1; SMN2 (0.43) | GPR84FFAR1FFAR4TSHR | |
| SCHEMBL2529447 | 0.78 | ACHE (0.47) | ACHENAAACYP4F2CYP4A11EPHX1 | |
| SCHEMBL2530032 | 0.78 | ACHE (0.47) | ACHENAAACYP4F2CYP4A11EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970137-B9 | COATING, ADHESIVE AND SEALANT COMPOSITIONS | INT COATINGS LTD (GB) | 2004-09-15 | — | — | EP | disclosed |
| US-6521716-B1 | Coating, adhesive and sealant compositions | AKZO NOBEL N.V. (NL) | 2003-02-18 | — | — | US | disclosed |
| EP-0970137-B1 | COATING, ADHESIVE AND SEALANT COMPOSITIONS | INT COATINGS LTD (GB) | 2002-06-12 | — | — | EP | disclosed |