Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MALT1 | Q9UDY8 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687149 | 0.84 | L3MBTL1 (0.43) | PTGS2L3MBTL1MALT1ALDH1A1 | |
| SCHEMBL6691333 | 0.77 | L3MBTL1 (0.43) | PTGS2L3MBTL1MALT1ALDH1A1KDM4E | |
| SCHEMBL6210243 | 0.77 | FFAR4 (0.44) | PTGS2ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6687455 | 0.75 | PTGS2 (0.42) | PTGS2L3MBTL1MALT1CYP1A2CYP2C9 | |
| SCHEMBL6680338 | 0.75 | L3MBTL1 (0.43) | PTGS2L3MBTL1MALT1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL6685425 | 0.74 | L3MBTL1 (0.43) | PTGS2L3MBTL1MALT1ALDH1A1CYP1A2 | |
| SCHEMBL6208572 | 0.74 | MALT1 (0.45) | PTGS2MALT1 | |
| SCHEMBL6210679 | 0.73 | BCL2 (0.43) | PTGS2LMNA | |
| SCHEMBL6685914 | 0.73 | L3MBTL1 (0.41) | PTGS2L3MBTL1MALT1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL6686163 | 0.73 | L3MBTL1 (0.42) | PTGS2L3MBTL1MALT1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |