Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685914 | 0.90 | L3MBTL1 (0.41) | L3MBTL1PTGS2MALT1OXTRALDH1A1 | |
| SCHEMBL6691333 | 0.90 | L3MBTL1 (0.43) | L3MBTL1PTGS2MALT1OXTRALDH1A1 | |
| Hydrochloric Acid SCHEMBL6686163 | 0.90 | L3MBTL1 (0.42) | L3MBTL1PTGS2MALT1OXTRPTGS1 | |
| SCHEMBL6687312 | 0.85 | L3MBTL1 (0.38) | L3MBTL1PTGS2MALT1OXTRALDH1A1 | |
| SCHEMBL6687145 | 0.84 | PTGS2 (0.44) | L3MBTL1PTGS2MALT1ALDH1A1 | |
| SCHEMBL6686978 | 0.83 | MEN1 (0.46) | L3MBTL1PTGS2OXTRALDH1A1PKM | |
| SCHEMBL6210243 | 0.77 | FFAR4 (0.44) | PTGS2ALDH1A1MKNK1MKNK2 | |
| SCHEMBL6680338 | 0.75 | L3MBTL1 (0.43) | L3MBTL1PTGS2MALT1OXTRALDH1A1 | |
| SCHEMBL6208574 | 0.75 | MDM2 (0.41) | PTGS2MALT1OXTRPTGS1 | |
| Hydrochloric Acid SCHEMBL6685425 | 0.75 | L3MBTL1 (0.43) | L3MBTL1PTGS2MALT1ALDH1A1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |