Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | OXTR | P30559 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685914 | 0.90 | L3MBTL1 (0.41) | L3MBTL1PTGS2MALT1OXTRKDM4E | |
| SCHEMBL6687149 | 0.90 | L3MBTL1 (0.43) | L3MBTL1PTGS2MALT1OXTRALDH1A1 | |
| Hydrochloric Acid SCHEMBL6686163 | 0.90 | L3MBTL1 (0.42) | L3MBTL1PTGS2MALT1OXTRPIK3CA | |
| SCHEMBL6687312 | 0.88 | L3MBTL1 (0.38) | L3MBTL1PTGS2MALT1OXTRALDH1A1 | |
| SCHEMBL6686978 | 0.83 | MEN1 (0.46) | L3MBTL1PTGS2OXTRKDM4EALDH1A1 | |
| SCHEMBL6687455 | 0.81 | PTGS2 (0.42) | L3MBTL1PTGS2MALT1PIK3CAP2RX7 | |
| SCHEMBL5147693 | 0.79 | MALT1 (0.41) | PTGS2MALT1PIK3CAPIK3CGP2RX7 | |
| SCHEMBL6682093 | 0.79 | MALT1 (0.41) | L3MBTL1PTGS2MALT1 | |
| SCHEMBL5152154 | 0.78 | OXTR (0.38) | PTGS2OXTRPIK3CAPIK3CGP2RX7 | |
| SCHEMBL6681832 | 0.78 | PTGS1 (0.57) | L3MBTL1PTGS2MALT1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |