Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 2/20 | 0.35 |
| ▸ | PRKACA | P17612 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | HIPK2 | Q9H2X6 | 2/20 | 0.35 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | ROS1 | P08922 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | PRKX | P51817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685914 | 0.89 | L3MBTL1 (0.41) | L3MBTL1PTGS2MALT1ALDH1A1OXTR | |
| SCHEMBL6691333 | 0.88 | L3MBTL1 (0.43) | L3MBTL1PTGS2MALT1ALDH1A1OXTR | |
| Hydrochloric Acid SCHEMBL6686163 | 0.86 | L3MBTL1 (0.42) | L3MBTL1PTGS2MALT1OXTR | |
| SCHEMBL6687149 | 0.85 | L3MBTL1 (0.43) | L3MBTL1PTGS2MALT1MKNK2ALDH1A1 | |
| SCHEMBL6686978 | 0.82 | MEN1 (0.46) | L3MBTL1PTGS2ALDH1A1OXTRMEN1 | |
| SCHEMBL6686275 | 0.78 | PTGS2 (0.43) | PTGS2MALT1ROCK2MAP4K4PIM1 | |
| SCHEMBL5150854 | 0.77 | MALT1 (0.44) | PTGS2MALT1 | |
| SCHEMBL5148769 | 0.77 | MALT1 (0.41) | PTGS2MALT1ROCK2MAP4K4PIM1 | |
| SCHEMBL6681738 | 0.76 | PTGS2 (0.58) | PTGS2MALT1 | |
| SCHEMBL5148798 | 0.74 | MALT1 (0.44) | PTGS2MALT1ROCK2MAP4K4PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004060367-A1 | IMIDAZOLE AND TRIAZOLE DERIVATIVES USEFUL AS SELECTIVE COX-1 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-07-22 | — | — | WO | disclosed |