Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690143 | 1.00 | GPR119 (0.41) | GPR119KMT2ALMNACYP1A2CYP2C9 | |
| SCHEMBL6687260 | 0.88 | ALDH1A1 (0.43) | GPR119LMNAHDAC1NPC1RAB9A | |
| SCHEMBL6687262 | 0.88 | ALDH1A1 (0.43) | GPR119LMNAHDAC1NPC1RAB9A | |
| SCHEMBL6685065 | 0.85 | GPR119 (0.42) | GPR119KMT2ALMNAHDAC1NPSR1 | |
| SCHEMBL6685070 | 0.85 | GPR119 (0.42) | GPR119KMT2ALMNAHDAC1NPSR1 | |
| SCHEMBL6685058 | 0.85 | GPR119 (0.42) | GPR119KMT2ALMNAHDAC1NPSR1 | |
| SCHEMBL6687420 | 0.84 | LMNA (0.47) | KMT2ALMNASMN1; SMN2PTPN1MAPT | |
| SCHEMBL6688055 | 0.84 | HDAC1 (0.40) | HDAC1NPC1PTPN1 | |
| SCHEMBL6688061 | 0.84 | HDAC1 (0.40) | HDAC1NPC1PTPN1 | |
| SCHEMBL6687419 | 0.84 | LMNA (0.47) | KMT2ALMNASMN1; SMN2PTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004089362-A1 | 2-CYANOPYRROLES AND THEIR ANALOGUES AS DDP-IV INHIBITORS | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |