Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL3 | Q96JM7 | 13/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 12/20 | 0.47 |
| ▸ | MBTD1 | Q05BQ5 | 7/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53BP1 | Q12888 | 3/20 | 0.36 |
| ▸ | L3MBTL4 | Q8NA19 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479690 | 0.85 | HRH3 (0.34) | L3MBTL3L3MBTL1MBTD1HRH3 | |
| SCHEMBL2480855 | 0.85 | HRH3 (0.34) | L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL695794 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL1900342 | 0.82 | ALDH1A1 (0.31) | — | |
| SCHEMBL188370 | 0.77 | — | — | |
| SCHEMBL1681276 | 0.76 | TSHR (0.37) | L3MBTL1HRH3 | |
| SCHEMBL18403928 | 0.70 | L3MBTL3 (0.46) | L3MBTL3L3MBTL1MBTD1CYP2D6CYP2C19 | |
| SCHEMBL187983 | 0.68 | ADRB1 (0.36) | — | |
| SCHEMBL2480196 | 0.68 | FAAH (0.32) | L3MBTL3L3MBTL1 | |
| SCHEMBL2483385 | 0.68 | CASP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004083173-A2 | KETOPIPERAZINE DERIVATIVES AS BRADYKININ ANTAGONISTS | MERCK & CO., INC. (US) | 2004-09-30 | — | — | WO | disclosed |