SCHEMBL6687971

SCHEMBL6687971

NC(=O)N(C(N)=O)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 2/20 0.42
GRIN3B O60391 2/20 0.42
GRIN1 Q05586 2/20 0.42
GRIN2A Q12879 2/20 0.42
GRIN2B Q13224 2/20 0.42
GRIN2C Q14957 2/20 0.42
GRIN3A Q8TCU5 2/20 0.42
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
THRB P10828 2/20 0.39
CYP2C9 P11712 1/20 0.39
EPHX1 P07099 2/20 0.38
NPC1 O15118 1/20 0.38
CRHBP P24387 1/20 0.38
HTT P42858 1/20 0.38
CRHR2 Q13324 1/20 0.38
MCOLN3 Q8TDD5 1/20 0.38
EPHX2 P34913 1/20 0.38
HSD11B1 P28845 1/20 0.37
SIGMAR1 Q99720 3/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6687969 0.89 THRB (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3071705 0.87 ALDH1A1 (0.37) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL22409653 0.81 ALDH1A1 (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6832697 0.78 CYP19A1 (0.33) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6830524 0.77 ALOX5 (0.30)
SCHEMBL28751556 0.77 GRIN2D (0.50) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL3081626 0.70 EPHX2 (0.47) EPHX1HTTEPHX2SIGMAR1POLB
SCHEMBL7401097 0.70 THRB (0.42) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL4914882 0.69 HSD11B1 (0.43) ALDH1A1TSHRHTTHSD11B1LMNA
SCHEMBL3059708 0.69 ALDH1A1 (0.44) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed