SCHEMBL6689

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17265478	0.87	LIPG (0.41)	LIPGLPLDGAT1F11F2
	SCHEMBL12091	0.84	TSHR (0.41)	BRD4ATMTDP1L3MBTL1TSHR
	SCHEMBL6838	0.82	L3MBTL1 (0.40)	BRD4ATMTDP1L3MBTL1TSHR
	SCHEMBL6690	0.80	LIPG (0.43)	LIPGLPLDGAT1TDP1
	SCHEMBL7480	0.78	LPAR1 (0.50)	DGAT1BRD4ATMTDP1L3MBTL1
	SCHEMBL6888	0.78	FFAR1 (0.47)	TSHR
	SCHEMBL13720569	0.77	LPAR1 (0.44)	BRD4ATMTDP1L3MBTL1TSHR
	SCHEMBL18597722	0.77	LPAR1 (0.37)	BRD4ATMTDP1L3MBTL1TSHR
	SCHEMBL1596	0.77	LPAR1 (0.52)	BRD4ATMTDP1L3MBTL1TSHR
	SCHEMBL7188	0.75	LPAR1 (0.38)	BRD4ATMTDP1L3MBTL1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.