Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.39 |
| ▸ | PTPN6 | P29350 | 5/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.39 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693313 | 0.83 | FFAR1 (0.46) | FFAR1ASIC3DRD2DRD3ALDH1A1 | |
| SCHEMBL45751 | 0.78 | KMT2A (0.42) | PTPN2PTPN1PTPN6PTPN11 | |
| SCHEMBL2813014 | 0.77 | KCNH2 (0.51) | FFAR1ASIC3DRD2DRD3MAPT | |
| SCHEMBL3684156 | 0.77 | KCNH2 (0.51) | FFAR1ASIC3DRD2DRD3MAPT | |
| SCHEMBL1312083 | 0.76 | ASIC3 (0.52) | FFAR1ASIC3DRD2DRD3HTR2C | |
| SCHEMBL2809245 | 0.76 | DRD2 (0.44) | FFAR1ASIC3DRD2DRD3TSHR | |
| SCHEMBL6696703 | 0.75 | PTPN2 (0.49) | FFAR1PTPN2PTPN1PTPN6PTPN11 | |
| SCHEMBL6696643 | 0.74 | MAOA (0.46) | ALDH1A1 | |
| SCHEMBL46934 | 0.74 | ALDH1A1 (0.38) | PTPN2PTPN1PTPN6PTPN11ALDH1A1 | |
| SCHEMBL6694265 | 0.74 | FFAR1 (0.62) | FFAR1ASIC3DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004106292-A1 | HALOETHYL UREA COMPOUNDS AND THEIR USE TO ATTENUATE, INHIBIT OR PREVENT NON-CANCEROUS PATHOGENIC CELLULAR PROLIFERATION AND DISEASES ASSOCIATED THEREWITH | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |
| WO-2004106291-A1 | HALOETHYL UREA COMPOUNDS AND THE USE THEREOF TO ATTENUATE, INHIBIT OR PREVENT CANCER CELL MIGRATION | IMOTEP INC. (CA) | 2004-12-09 | — | — | WO | disclosed |