Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSS | P25774 | 2/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | CTSD | P07339 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.40 |
| ▸ | EML4 | Q9HC35 | 2/20 | 0.40 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4800967 | 0.83 | CTSL (0.61) | CTSLCTSSCTSKCTSDBACE1 | |
| SCHEMBL6690120 | 0.80 | TAS1R3 (0.39) | CTSLCTSSCTSKLRRK2EPHX1 | |
| SCHEMBL6690323 | 0.79 | CTSS (0.40) | CTSLCTSSCTSKEPHX1SMN1; SMN2 | |
| SCHEMBL6693994 | 0.78 | CTSS (0.42) | CTSLCTSSCTSKEPHX1LMNA | |
| SCHEMBL4798248 | 0.76 | CTSL (0.46) | CTSLCTSSCTSKCCR3LMNA | |
| SCHEMBL6694461 | 0.76 | ALDH1A1 (0.54) | CTSLCTSSCTSKEPHX1SMN1; SMN2 | |
| SCHEMBL5499714 | 0.75 | ALDH1A1 (0.52) | CTSLCTSSCTSKEPHX1SMN1; SMN2 | |
| SCHEMBL4800960 | 0.75 | CTSL (0.47) | CTSLCTSSCTSKCTSDBACE1 | |
| SCHEMBL6693529 | 0.74 | TP53 (0.48) | TSHRMEN1KMT2AKDM4E | |
| SCHEMBL6686249 | 0.74 | KMT2A (0.44) | EPHX1LMNASMN1; SMN2TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |