Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 14/20 | 0.40 |
| ▸ | CTSL | P07711 | 12/20 | 0.40 |
| ▸ | CTSK | P43235 | 10/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693994 | 0.90 | CTSS (0.42) | CTSSCTSLCTSKEPHX1ALDH1A1 | |
| SCHEMBL6694461 | 0.88 | ALDH1A1 (0.54) | CTSSCTSLCTSKEPHX1ALDH1A1 | |
| SCHEMBL5499714 | 0.86 | ALDH1A1 (0.52) | CTSSCTSLCTSKEPHX1ALDH1A1 | |
| SCHEMBL4797862 | 0.80 | CTSS (0.48) | CTSSCTSLCTSKMETAP2 | |
| SCHEMBL6689442 | 0.79 | CTSL (0.52) | CTSSCTSLCTSKEPHX1ALDH1A1 | |
| SCHEMBL6693529 | 0.79 | TP53 (0.48) | TSHR | |
| SCHEMBL6686249 | 0.79 | KMT2A (0.44) | EPHX1ALDH1A1SMN1; SMN2TSHRNPC1 | |
| SCHEMBL6690120 | 0.76 | TAS1R3 (0.39) | CTSSCTSLCTSKEPHX1TSHR | |
| SCHEMBL6688117 | 0.76 | TAS1R3 (0.45) | CTSSCTSLCTSKEPHX1ALDH1A1 | |
| SCHEMBL6686976 | 0.75 | SMN1; SMN2 (0.39) | CTSSCTSLCTSKALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |