Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 10/20 | 0.40 |
| ▸ | MMP2 | P08253 | 9/20 | 0.40 |
| ▸ | MMP1 | P03956 | 7/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 2/20 | 0.38 |
| ▸ | PLG | P00747 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6693432 | 0.87 | CTSS (0.41) | MMP3MMP2MMP1CTSSCTSL | |
| SCHEMBL6693574 | 0.84 | CTSS (0.42) | MMP3MMP2MMP1CTSSCTSL | |
| SCHEMBL6690633 | 0.81 | USP30 (0.40) | MMP1CTSSCTSL | |
| SCHEMBL6690630 | 0.81 | USP30 (0.41) | MMP3MMP2MMP1CTSSCTSL | |
| SCHEMBL6686203 | 0.81 | BMP1 (0.42) | MMP3MMP2MMP1CTSSCTSL | |
| SCHEMBL6686240 | 0.80 | CTSS (0.41) | CTSSCTSLPRSS1 | |
| SCHEMBL6690326 | 0.80 | CTSS (0.45) | MMP3MMP2MMP1CTSSCTSL | |
| SCHEMBL5497651 | 0.80 | CTSS (0.40) | CTSSCTSL | |
| SCHEMBL6690347 | 0.79 | CTSS (0.45) | CTSSCTSL | |
| SCHEMBL6696331 | 0.79 | CTSS (0.37) | CTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |