SCHEMBL6696331 — predicted protein targets

Predicted protein targets (top 16)

	gene	UniProt	supporting neighbours	confidence
▸	CTSS	P25774	6/20	0.37

▸	CTSL	P07711	5/20	0.37

▸	METAP2	P50579	3/20	0.36

▸	METAP1	P53582	3/20	0.36

▸	MC3R	P41968	2/20	0.36

▸	MC4R	P32245	1/20	0.36

▸	RAB9A	P51151	2/20	0.35

▸	NPC1	O15118	1/20	0.35

▸	OPRK1	P41145	1/20	0.35

▸	DPEP1	P16444	1/20	0.35

▸	CIT	O14578	1/20	0.35

▸	PIM1	P11309	1/20	0.34

▸	PIM2	Q9P1W9	1/20	0.34

▸	POLB	P06746	1/20	0.33

▸	SMN1; SMN2	Q16637	1/20	0.33

▸	GCK	P35557	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5497651	0.89	CTSS (0.40)	CTSSCTSLMETAP2METAP1RAB9A
SCHEMBL6693432	0.83	CTSS (0.41)	CTSSCTSL
SCHEMBL6688690	0.82	OPRL1 (0.34)	CTSLMC3RRAB9ANPC1PIM1
SCHEMBL5505729	0.82	OPRL1 (0.34)	CTSLMC3RRAB9ANPC1PIM1
SCHEMBL6689460	0.79	MMP3 (0.40)	CTSSCTSL
SCHEMBL6690381	0.79	CTSS (0.46)	CTSSCTSL
SCHEMBL6690326	0.79	CTSS (0.45)	CTSSCTSL
SCHEMBL6690630	0.78	USP30 (0.41)	CTSSCTSL
SCHEMBL6690633	0.78	USP30 (0.40)	CTSSCTSL
SCHEMBL6686203	0.78	BMP1 (0.42)	CTSSCTSLNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2004112709-A2	INHIBITORS OF CATHEPSIN S	IRM LLC (BM)	2004-12-29	—	—	WO	disclosed