Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.50 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 6/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 6/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 6/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19900413 | 0.77 | CHRNB2 (0.61) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL20718324 | 0.73 | CHRNB2 (0.66) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL9845087 | 0.72 | GSR (0.43) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL9845084 | 0.72 | GSR (0.43) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL2401455 | 0.71 | CHRNB2 (0.56) | CHRNB2CHRNA4SLC7A5SLC1A1SLC1A3 | |
| SCHEMBL199134 | 0.71 | SLC7A5 (0.58) | SLC7A5SLC1A1SLC1A3SLC1A2GRIK1 | |
| SCHEMBL3383446 | 0.71 | SLC1A2 (0.64) | SLC7A5SLC1A1SLC1A3SLC1A2CHRM1 | |
| SCHEMBL13637616 | 0.71 | CHRNB2 (0.63) | CHRNB2CHRNA4CHRM2CHRM4CHRM5 | |
| SCHEMBL18229129 | 0.71 | SLC1A2 (0.64) | SLC7A5SLC1A1SLC1A3SLC1A2CHRM1 | |
| SCHEMBL18229136 | 0.71 | SLC1A2 (0.64) | SLC7A5SLC1A1SLC1A3SLC1A2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004070009-A2 | TARGETED MULTIVALENT MACROMOLECULES | TARGESOME INC. (US) | 2004-08-19 | — | — | WO | disclosed |
| EP-1401818-A2 | TARGETED MULTIVALENT MACROMOLECULES | Targesome, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| US-20030133972-A1 | Targeted multivalent macromolecules | TARGESOME, INC. | 2003-07-17 | — | — | US | disclosed |
| US-20030129223-A1 | Therapeutic agents, comprising a linking carrier, a therapeutic entity associated with the linking carrier, and atleast one targeting entity | TARGESOME, INC. | 2003-07-10 | — | — | US | disclosed |
| WO-2002096367-A2 | TARGETED MULTIVALENT MACROMOLECULES | TARGESOME, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030133972-A1 | Targeted multivalent macromolecules | CLTB, ILK, CD44 | CHRNB2 2493/4885CHRNA4 4159/4885SLC7A5 1848/4885 |
| US-20030129223-A1 | Therapeutic agents, comprising a linking carrier, a therapeutic entity associated with the linking carrier, and atleast one targeting entity | CD47, TSG101, ILK | CHRNB2 4165/4885CHRNA4 4756/4885SLC7A5 2213/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.