Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.56 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 7/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.42 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.39 |
| ▸ | GRM8 | O00222 | 1/20 | 0.39 |
| ▸ | GRM6 | O15303 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9845084 | 0.79 | GSR (0.43) | SLC1A1SLC1A3SLC1A2GRIK1GRIK2 | |
| SCHEMBL9845087 | 0.79 | GSR (0.43) | SLC1A1SLC1A3SLC1A2GRIK1GRIK2 | |
| SCHEMBL1782303 | 0.77 | CHRNB2 (0.68) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL17852152 | 0.77 | ACHE (0.54) | ACHE | |
| SCHEMBL15469777 | 0.76 | CHRNB2 (0.53) | CHRNB2CHRNB4CHRNA3CHRNA4ACHE | |
| SCHEMBL16674069 | 0.76 | ACHE (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4MEN1 | |
| SCHEMBL23385458 | 0.76 | ACHE (0.53) | NOD1ACHE | |
| SCHEMBL23608137 | 0.76 | ACHE (0.53) | NOD1ACHE | |
| SCHEMBL23607693 | 0.76 | ACHE (0.53) | NOD1ACHE | |
| SCHEMBL29714769 | 0.76 | SLC1A1 (0.46) | SLC1A1SLC1A3SLC1A2GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130211078-A1 | PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A CARBAMATE INTERMEDIATE | NOVUS INTERNATIONAL INC. (US) | 2013-08-15 | — | — | US | disclosed |
| US-8476427-B2 | Preparation of methionine or selenomethionine from homoserine via a carbamate intermediate | NOVUS INTERNATIONAL, INC. (US) | 2013-07-02 | — | — | US | disclosed |
| US-20110224430-A1 | PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A CARBAMATE INTERMEDIATE | NOVUS INTERNATIONAL INC. (US) | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110224430-A1 | PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A CARBAMATE INTERMEDIATE | MTR, CTH, BHMT2 | CHRNB2 3321/4885CHRNB4 3353/4885CHRNA3 3219/4885 |
| US-20130211078-A1 | PREPARATION OF METHIONINE OR SELENOMETHIONINE FROM HOMOSERINE VIA A CARBAMATE INTERMEDIATE | MTR, CTH, BHMT2 | CHRNB2 3321/4885CHRNB4 3353/4885CHRNA3 3219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.