Known targets — ChEMBL curated mechanism
POLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PRIM1PRIM2
The experimentally established mechanism targets of Cytidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MTOR | P42345 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.57 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.57 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.53 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.53 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.53 |
| ▸ | STAT6 | P42226 | 1/20 | 0.53 |
| ▸ | PI4KA | P42356 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cytidine SCHEMBL18281061 | 0.86 | LMNA (0.55) | LMNATHRBMTORMDM2NCOA1 | |
| Adenosine SCHEMBL1179624 | 0.84 | ADORA3 (0.75) | LMNATHRBMTORMDM2NCOA1 | |
| Adenosine SCHEMBL15753064 | 0.84 | ADORA3 (0.75) | LMNATHRBMTORMDM2NCOA1 | |
| Adenosine SCHEMBL624354 | 0.84 | ADORA3 (0.75) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL199259 | 0.84 | ADORA1 (0.51) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Vidarabine SCHEMBL1684018 | 0.83 | ADORA3 (0.74) | LMNATHRBMTORMDM2NCOA1 | |
| Vidarabine SCHEMBL11164529 | 0.83 | ADORA3 (0.74) | LMNATHRBMTORMDM2NCOA1 | |
| Phosphoric Acid SCHEMBL216583 | 0.83 | ADORA1 (0.50) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Pyrophosphoric Acid SCHEMBL668584 | 0.80 | ADORA1 (0.52) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 | |
| Adenosine SCHEMBL14783412 | 0.80 | P2RY2 (0.65) | ADORA1SMN1; SMN2ADORA3DPP4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004110964-A2 | ENCODED MOLECULES BY TRANSLATION (EMT) | NUEVOLUTION A/S (DK) | 2004-12-23 | — | — | WO | disclosed |