Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | GNRHR | P30968 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | AKT1 | P31749 | 2/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CKS1B | P61024 | 1/20 | 0.30 |
| ▸ | SKP1 | P63208 | 1/20 | 0.30 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689803 | 0.86 | SIGMAR1 (0.39) | SIGMAR1CTSSCTSLRAB9A | |
| SCHEMBL6690790 | 0.81 | SYK (0.34) | TACR2NPY5RCTSSSYKCTSL | |
| SCHEMBL6694083 | 0.77 | CCNT1 (0.33) | — | |
| SCHEMBL8286606 | 0.72 | IDO1 (0.53) | TACR2IDO1CTSLL3MBTL1 | |
| SCHEMBL4973253 | 0.71 | CTSS (0.42) | SIGMAR1NPY5RCTSSSYKCTSL | |
| SCHEMBL12696399 | 0.69 | NQO2 (0.44) | BCHEIDO1EPHX2 | |
| SCHEMBL6688100 | 0.68 | CTSS (0.41) | SIGMAR1CTSSCTSLRAB9A | |
| SCHEMBL20505740 | 0.67 | EPHX2 (0.50) | BCHEIDO1EPHX2 | |
| SCHEMBL29572544 | 0.67 | EPHX2 (0.50) | BCHEIDO1EPHX2 | |
| SCHEMBL6686186 | 0.66 | CCNT1 (0.36) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |