Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.32 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 3/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.31 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.31 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | TACR2 | P21452 | 1/20 | 0.31 |
| ▸ | KLK7 | P49862 | 1/20 | 0.31 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688100 | 0.85 | CTSS (0.41) | CTSLCTSSRAB9AKMT2ACTSK | |
| SCHEMBL6689978 | 0.81 | SIGMAR1 (0.33) | SYKCTSLNPY5RCTSSL3MBTL1 | |
| SCHEMBL6685441 | 0.78 | CTSS (0.45) | CTSLCTSSCTSK | |
| SCHEMBL4973253 | 0.74 | CTSS (0.42) | SYKCTSLNPY5RCTSSGPR119 | |
| SCHEMBL6690009 | 0.71 | CTSS (0.46) | CTSLCTSSPPARARAB9ACTSK | |
| SCHEMBL6688064 | 0.70 | CTSS (0.42) | CTSLCTSSRAB9AKMT2ACTSK | |
| SCHEMBL6689803 | 0.69 | SIGMAR1 (0.39) | CTSLCTSSRAB9AKMT2A | |
| SCHEMBL8286606 | 0.68 | IDO1 (0.53) | CTSLL3MBTL1TACR2KMT2A | |
| SCHEMBL6694455 | 0.68 | CTSS (0.39) | CTSLCTSSGPR119EPHX2TACR2 | |
| SCHEMBL6686227 | 0.67 | CTSS (0.40) | CTSLCTSSPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |