Sugi Predict

Sugi Predict / Compounds / SCHEMBL256797

SCHEMBL256797

SCHEMBL256797

Cc1ccccc1OCC1CC1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 1/20 0.65
▸ GLA P06280 1/20 0.65
▸ RIPK1 Q13546 1/20 0.57
▸ PKM P14618 1/20 0.51
▸ HTR2C P28335 2/20 0.47
▸ MEN1 O00255 3/20 0.46
▸ KMT2A Q03164 3/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ CYP2D6 P10635 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45
▸ KDM4E B2RXH2 1/20 0.44
▸ CYP1A2 P05177 1/20 0.44
▸ SCN4A P35499 1/20 0.43
▸ LMNA P02545 2/20 0.42
▸ SMN1; SMN2 Q16637 1/20 0.42
▸ NISCH Q9Y2I1 1/20 0.42
▸ PDE10A Q9Y233 1/20 0.42
▸ BRD4 O60885 1/20 0.42
▸ NPY1R P25929 1/20 0.42
▸ NPY2R P49146 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10066572 1.00 ALDH1A1 (0.65) ALDH1A1GLARIPK1PKMHTR2C
SCHEMBL24224814 0.92 ALDH1A1 (0.61) ALDH1A1GLARIPK1PKMHTR2C
SCHEMBL5673940 0.91 ALDH1A1 (0.59) ALDH1A1GLARIPK1PKMHTR2C
SCHEMBL2240409 0.88 ALDH1A1 (0.56) ALDH1A1GLARIPK1PKMHTR2C
Hydrochloric Acid SCHEMBL1474902 0.86 ALDH1A1 (0.54) ALDH1A1GLARIPK1PKMHTR2C
SCHEMBL18964615 0.83 ALDH1A1 (0.69) ALDH1A1GLARIPK1PKMMEN1
SCHEMBL5822620 0.82 ALDH1A1 (0.54) ALDH1A1GLARIPK1PKMHTR2C
SCHEMBL879145 0.82 RIPK1 (0.47) ALDH1A1GLARIPK1PKMHTR2C
SCHEMBL23493028 0.82 RIPK1 (0.47) ALDH1A1GLARIPK1PKMHTR2C
SCHEMBL24153922 0.82 RIPK1 (0.47) ALDH1A1GLARIPK1HTR2CPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2023-05-18 — — US disclosed
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2023-05-18 — — US disclosed
WO-2021151919-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2021-08-05 — — WO disclosed
EP-2900654-B1 TETRAZOLINONE COMPOUNDS AND THEIR USE AS PESTICIDES SUMITOMO CHEMICAL CO (JP) 2017-05-17 — — EP disclosed
US-9493438-B2 4,4-difluoro-piperidine-compounds ROTTAPHARM S.R.L. (IT) 2016-11-15 — — US disclosed
EP-2820007-B1 4,4-DIFLUORO-PIPERIDINE-COMPOUNDS Rottapharm Biotech Srl (IT) 2016-04-20 — — EP disclosed
CN-105164130-A Dihydro-pyrrolopyridone bromodomain inhibitors ABBVIE INC 2015-12-16 — — CN disclosed
US-20150051226-A1 4,4-DIFLUORO-PIPERIDINE-COMPOUNDS ROTTAPHARM S.P.A. (IT) 2015-02-19 — — US disclosed
US-8895552-B2 Cyclic amide derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2014-11-25 — — US disclosed
US-8895552-B2 Cyclic amide derivative SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) 2014-11-25 — — US disclosed
US-8119225-B2 Copper clad laminate, prepreg and method of reducing signal loss Ventec Electronics (Suzhou) company limited (CN) 2012-02-21 — — US disclosed
US-20110294786-A1 SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-12-01 — — US disclosed
US-20110294786-A1 SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES MITSUBISHI TANABE PHARMA CORPORATION (JP) 2011-12-01 — — US disclosed
US-20100248569-A1 COPPER CLAD LAMINATE, PREPREG AND METHOD OF REDUCING SIGNAL LOSS Ventec Electronics (Suzhou) company limited (CN) 2010-09-30 — — US disclosed
US-20090036427-A1 SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES SANOFI-AVENTIS (FR) 2009-02-05 — — US disclosed
US-20090036427-A1 SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES SANOFI-AVENTIS (FR) 2009-02-05 — — US disclosed
WO-2007146124-A2 DEUTERATED TADALAFIL DERIVATIVES AUSPEX PHARMACEUTICALS, INC. (US) 2007-12-21 — — WO disclosed
US-20070219216-A1 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2007-09-20 — — US disclosed
US-20070219216-A1 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists RANBAXY LABORATORIES LIMITED (IN) 2007-09-20 — — US disclosed
WO-2007057790-A2 SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES SANOFI-AVENTIS (FR) 2007-05-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110294786-A1 SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES GSK3B, GSK3A, PSEN1 ALDH1A1 1204/4885GLA 671/4885RIPK1 1318/4885
US-20070219216-A1 1-Alkylpiperazinyl-Pyrrolidin-2,5-Dione Derivatives as Adrenergic Receptor Antagonists ADRA1D, ADRA1A, ADRB1 ALDH1A1 51/4885GLA 2202/4885RIPK1 4325/4885
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS PNPO, HPD, PDXK ALDH1A1 1673/4885GLA 1620/4885RIPK1 2027/4885
US-20150051226-A1 4,4-DIFLUORO-PIPERIDINE-COMPOUNDS SLCO4C1, PAICS, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 ALDH1A1 1187/4885GLA 3443/4885RIPK1 4873/4885
US-20090036427-A1 SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES GSK3B, GSK3A, PSEN1 ALDH1A1 1204/4885GLA 671/4885RIPK1 1318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.