Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 5/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685716 | 0.88 | KDM4E (0.47) | EPHX1KDM4EALDH1A1POLBEPHX2 | |
| SCHEMBL6693491 | 0.84 | NPC1 (0.42) | KDM4EALDH1A1EPHX2 | |
| SCHEMBL6688042 | 0.83 | HTR7 (0.39) | ALDH1A1CYP2C9 | |
| SCHEMBL6685681 | 0.83 | EPHX2 (0.48) | EPHX1ALDH1A1POLBEPHX2CYP2C9 | |
| SCHEMBL6688679 | 0.82 | NPC1 (0.39) | EPHX1ALDH1A1POLBEPHX2CYP2C9 | |
| SCHEMBL6690552 | 0.81 | TSHR (0.51) | EPHX1 | |
| SCHEMBL6686627 | 0.80 | NPC1 (0.38) | KDM4EALDH1A1CYP2C9 | |
| SCHEMBL6686695 | 0.80 | MEN1 (0.40) | CFDKDM4EALDH1A1POLB | |
| SCHEMBL6685923 | 0.80 | RAB9A (0.38) | EPHX1POLB | |
| SCHEMBL6687352 | 0.79 | MAPT (0.45) | ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |