Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | CCR3 | P51677 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.36 |
| ▸ | EML4 | Q9HC35 | 1/20 | 0.35 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.35 |
| ▸ | GRK2 | P25098 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690542 | 0.88 | RORC (0.41) | MEN1KMT2AALDH1A1CA2ALDH3A1 | |
| SCHEMBL6693491 | 0.85 | NPC1 (0.42) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6688679 | 0.84 | NPC1 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6685681 | 0.84 | EPHX2 (0.48) | MEN1KMT2AALDH1A1LMNAMAPT | |
| SCHEMBL6688042 | 0.84 | HTR7 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL6686627 | 0.83 | NPC1 (0.38) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6690552 | 0.82 | TSHR (0.51) | KMT2ACTSLCTSKCCR3 | |
| SCHEMBL6693570 | 0.81 | CA2 (0.44) | MEN1KMT2AALDH1A1CA12CA1 | |
| SCHEMBL6689992 | 0.80 | CFD (0.41) | ALDH1A1KDM4ECFDPOLB | |
| SCHEMBL6687208 | 0.79 | TRPA1 (0.35) | MEN1KMT2AALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |