SCHEMBL669072

SCHEMBL669072

Oc1ccc(F)c(O)c1F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA3 P07451 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
ERN1 O75460 1/20 0.39
PIM1 P11309 1/20 0.38
HSD17B14 Q9BPX1 1/20 0.37
HSD17B10 Q99714 2/20 0.36
TSHR P16473 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MPI P34949 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ADRA2A P08913 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35
ADRA1A P35348 1/20 0.35
ADRB2 P07550 1/20 0.35
ADRA1B P35368 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29766667 1.00 CA3 (0.42) CA3CA6CA5ACA9CA14
SCHEMBL78147 0.81 ERN1 (0.42) CA3CA6CA5ACA9CA14
SCHEMBL30368289 0.81 ERN1 (0.42) CA3CA6CA5ACA9CA14
SCHEMBL6351040 0.79 CA6 (0.43) CA3CA6CA5ACA9CA14
SCHEMBL155976 0.79 CES2 (0.46) CA3CA6CA5ACA9CA14
SCHEMBL5512576 0.77 ERN1 (0.48) CA3CA6CA5ACA9CA14
SCHEMBL1512796 0.77 PIM1 (0.41) CA3CA6CA5ACA9CA14
SCHEMBL29987655 0.77 PIM1 (0.41) CA3CA6CA5ACA9CA14
SCHEMBL5506954 0.77 ADRA2A (0.45) CA3CA6CA5ACA9CA14
SCHEMBL8597374 0.77 CES2 (0.44) CA3CA6CA5ACA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 125 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108250384-B Simple method for preparing fluorine-containing polyurethane monodisperse microspheres with high yield 济南大学 2020-09-01 CN claimed
CN-108250384-A A kind of high yield prepares the short-cut method of fluorochemical urethane mono-dispersion microballoon 济南大学 2018-07-06 CN claimed
EP-1946102-A1 COUMARIN-BASED AMINO ACIDS FOR USE IN ENZYME ACTIVITY AND SUBSTRATE SPECIFICITY ASSAYS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2008-07-23 EP claimed
US-20070031892-A1 Novel coumarin-based amino acids for use in enzyme activity and substrate specificity assays USC 2007-02-08 US claimed
WO-2007014326-A1 COUMARIN-BASED AMINO ACIDS FOR USE IN ENZYME ACTIVITY AND SUBSTRATE SPECIFICITY ASSAYS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 2007-02-01 WO claimed
EP-0853647-B1 FLUORINATED XANTHENE DERIVATIVES MOLECULAR PROBES INC (US) 2004-10-13 EP claimed
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US claimed
EP-0853647-A1 FLUORINATED XANTHENE DERIVATIVES Molecular Probes Inc. (US) 1998-07-22 EP claimed
WO-1997039064-A1 FLUORINATED XANTHENE DERIVATIVES MOLECULAR PROBES, INC. (US) 1997-10-23 WO claimed
CN-1040024-A 2, the 3-Difluorophenol derivatives MERCK PATENT GMBH (DE) 1990-02-28 CN claimed
US-20260078141-A1 8-FLUORO-4-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE, BIOLOGICAL STERILIZATION INDICATOR INCLUDING THE SAME AND ITS USE IN A METHOD OF DETERMINING EFFICACY OF A STERILIZATION PROCESS SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2026-03-19 US disclosed
EP-4676919-A1 MONOFLUORINATED COUMARIN FLUOROPHORES AND USES THEREOF Ohio State Innovation Foundation (US) 2026-01-14 EP disclosed
US-12486301-B2 8-fluoro-4-alkylumbelliferyl α-D-glucopyranoside, biological sterilization indicator including the same and its use in a method of determining efficacy of a sterilization process SOLVENTUM INTELLECTUAL PROPERTIES COMPANY (US) 2025-12-02 US disclosed
US-20250042911-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF SPARK BIOPHARMA, INC. (KR) 2025-02-06 US disclosed
US-20240426847-A1 COMPOSITIONS AND METHODS FOR THE DETERMINATION OF SODIUM CONCENTRATION THE UNIVERSITY OF CHICAGO 2024-12-26 US disclosed
US-6229055-B1 SYNTHESIS OF FLUORINATED RESORCINOL WHICH IS USEFUL IN THE PREPARATION OF FLUORINATED FLUORESCEIN AND RHODOL DYES SUITABLE FOR USE AS TRACERS, LABELS, OR INTERMEDIATES MOLECULAR PROBES, INC. 2001-05-08 US disclosed
US-6162931-A Fluorinated xanthene derivatives MOLECULAR PROBES, INC. (US) 2000-12-19 US disclosed
US-5830912-A Derivatives of 6,8-difluoro-7-hydroxycoumarin MOLECULAR PROBES, INC. (US) 1998-11-03 US disclosed
CN-1040024-A 2, the 3-Difluorophenol derivatives MERCK PATENT GMBH (DE) 1990-02-28 CN disclosed
CN-1040024-A 2, the 3-Difluorophenol derivatives MERCK PATENT GMBH (DE) 1990-02-28 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250042911-A1 NOVEL BENZOPYRAN DERIVATIVE AND USE THEREOF MYD88, MYADM, CD14 CA3 4525/4885CA6 3401/4885CA5A 1272/4885
US-20260078141-A1 8-FLUORO-4-ALKYLUMBELLIFERYL ALPHA-D-GLUCOPYRANOSIDE, BIOLOGICAL STERILIZATION INDICATOR INCLUDING THE SAME AND ITS USE IN A METHOD OF DETERMINING EFFICACY OF A STERILIZATION PROCESS ALPG, UNG, UGDH CA3 2021/4885CA6 1217/4885CA5A 3898/4885
US-12486301-B2 8-fluoro-4-alkylumbelliferyl α-D-glucopyranoside, biological sterilization indicator including the same and its use in a method of determining efficacy of a sterilization process ALPG, UNG, UGDH CA3 1018/4885CA6 1196/4885CA5A 2996/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.