Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | CCNC | P24863 | 1/20 | 0.35 |
| ▸ | CDK8 | P49336 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.32 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6695952 | 0.83 | HDAC1 (0.38) | — | |
| SCHEMBL6692917 | 0.80 | IKBKB (0.31) | — | |
| SCHEMBL6692767 | 0.79 | PDE2A (0.34) | CSNK2A1 | |
| SCHEMBL6691418 | 0.79 | IKBKB (0.30) | — | |
| SCHEMBL6688882 | 0.77 | HTR6 (0.33) | — | |
| SCHEMBL6686771 | 0.73 | KDM4E (0.32) | KDM4E | |
| SCHEMBL6833887 | 0.61 | ALDH1A1 (0.39) | NPC1TP53 | |
| SCHEMBL363391 | 0.59 | NOTUM (0.56) | MTNR1AMTNR1BCCNCCDK8POLB | |
| SCHEMBL24159303 | 0.58 | TBXAS1 (0.35) | MTNR1AMTNR1BCCNCCDK8CYP2C9 | |
| SCHEMBL27326917 | 0.57 | NR4A2 (0.36) | MTNR1AMTNR1BCCNCCDK8CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004072078-A1 | PYRAZOLOTRIAZINE DERIVATIVES, METHODS FOR PRODUCTION AND USES THEREOF | UNIVERSITE LOUIS PASTEUR (FR) | 2004-08-26 | — | — | WO | claimed |
| WO-2004072078-A1 | PYRAZOLOTRIAZINE DERIVATIVES, METHODS FOR PRODUCTION AND USES THEREOF | UNIVERSITE LOUIS PASTEUR (FR) | 2004-08-26 | — | — | WO | disclosed |