Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692767 | 0.79 | PDE2A (0.34) | — | |
| SCHEMBL6833888 | 0.73 | CRHR1 (0.45) | ALDH1A1KMT2ATP53L3MBTL1NPC1 | |
| SCHEMBL6687391 | 0.68 | RAB9A (0.40) | ALDH1A1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6692917 | 0.67 | IKBKB (0.31) | — | |
| SCHEMBL6691418 | 0.66 | IKBKB (0.30) | — | |
| SCHEMBL9878707 | 0.63 | SLC2A1 (0.47) | ALDH1A1KMT2ANPC1LMNAHTT | |
| SCHEMBL4925190 | 0.62 | LMNA (0.69) | ALDH1A1KMT2AHTR2CTP53NPC1 | |
| SCHEMBL6691233 | 0.61 | MTNR1A (0.35) | TP53NPC1 | |
| SCHEMBL4180510 | 0.61 | KDR (0.46) | ALDH1A1KMT2AL3MBTL1NPC1LMNA | |
| SCHEMBL6688882 | 0.61 | HTR6 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004072078-A1 | PYRAZOLOTRIAZINE DERIVATIVES, METHODS FOR PRODUCTION AND USES THEREOF | UNIVERSITE LOUIS PASTEUR (FR) | 2004-08-26 | — | — | WO | disclosed |