Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 2/20 | 0.34 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | CHUK | O15111 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692917 | 0.85 | IKBKB (0.31) | IKBKBCHUK | |
| SCHEMBL6691418 | 0.84 | IKBKB (0.30) | IKBKBCHUK | |
| SCHEMBL6688882 | 0.80 | HTR6 (0.33) | IKBKBCHUK | |
| SCHEMBL6833887 | 0.79 | ALDH1A1 (0.39) | — | |
| SCHEMBL6691233 | 0.79 | MTNR1A (0.35) | CSNK2A1 | |
| SCHEMBL6798351 | 0.69 | HRH1 (0.37) | — | |
| SCHEMBL6833888 | 0.69 | CRHR1 (0.45) | — | |
| SCHEMBL9822411 | 0.67 | PDE2A (0.42) | PDE2A | |
| SCHEMBL3898819 | 0.67 | PDE2A (0.33) | PDE2A | |
| SCHEMBL9822430 | 0.67 | PDE2A (0.42) | PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004072078-A1 | PYRAZOLOTRIAZINE DERIVATIVES, METHODS FOR PRODUCTION AND USES THEREOF | UNIVERSITE LOUIS PASTEUR (FR) | 2004-08-26 | — | — | WO | claimed |
| WO-2004072078-A1 | PYRAZOLOTRIAZINE DERIVATIVES, METHODS FOR PRODUCTION AND USES THEREOF | UNIVERSITE LOUIS PASTEUR (FR) | 2004-08-26 | — | — | WO | disclosed |