SCHEMBL6691263

SCHEMBL6691263

O=C(CCl)Oc1cccc(Cl)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.47
RXRA P19793 1/20 0.46
RXRB P28702 1/20 0.46
RXRG P48443 1/20 0.46
KDM4E B2RXH2 2/20 0.45
WDR5 P61964 1/20 0.45
OGG1 O15527 1/20 0.44
FAAH O00519 1/20 0.44
FFAR1 O14842 1/20 0.43
PPARG P37231 1/20 0.43
PPARD Q03181 1/20 0.43
NPC1 O15118 1/20 0.43
F2 P00734 1/20 0.43
RAB9A P51151 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
ACHE P22303 1/20 0.42
MEN1 O00255 1/20 0.42
KMT2A Q03164 1/20 0.42
FKBP1A P62942 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3450853 0.87 BCHE (0.48) BCHERXRARXRBRXRGKDM4E
SCHEMBL19331388 0.84 WDR5 (0.47) BCHERXRARXRBRXRGKDM4E
SCHEMBL11680457 0.84 ACHE (0.61) BCHERXRARXRBRXRGKDM4E
SCHEMBL11251384 0.83 MEN1 (0.44) RXRARXRBACHEMEN1KMT2A
Hydrochloric Acid SCHEMBL29089661 0.82 WDR5 (0.46) BCHERXRARXRBRXRGKDM4E
SCHEMBL28847227 0.82 WDR5 (0.46) BCHERXRARXRBRXRGKDM4E
SCHEMBL4644019 0.81 CYP3A4 (0.59) ACHEMEN1KMT2A
SCHEMBL28468513 0.81 OGG1 (0.48) BCHERXRARXRBRXRGKDM4E
SCHEMBL30012328 0.81 NPC1 (0.43) BCHERXRARXRBRXRGKDM4E
SCHEMBL27348590 0.81 FAAH (0.50) KDM4EFAAHACHEKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0950669-B1 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM & HAAS (US) 2004-09-08 EP disclosed
US-6306991-B1 TWO PART COATING COMPOSITION WITH TWO CONTAINERS, OXIDATIVE POLYMERS WITH CROSSLINKABLE FUNCTIONAL GROUPS ROHM AND HAAS COMPANY 2001-10-23 US disclosed
US-6149977-A CONTACTING THE OXIDATIVE POLYMER WITH A CATALYTIC AMOUNT OF AN OXIDIZING ENZYME, SUCH AS HORSERADISH PEROXIDASE. ROHM AND HAAS COMPANY (US) 2000-11-21 US disclosed
EP-0950669-A2 Method of catalytic crosslinking of polymers and two-pack composition used therein ROHM AND HAAS COMPANY (US) 1999-10-20 EP disclosed