Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | AURKA | O14965 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680293 | 0.90 | L3MBTL1 (0.71) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6691306 | 0.86 | AURKA (0.66) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6688390 | 0.86 | L3MBTL1 (0.62) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6689594 | 0.85 | L3MBTL1 (0.64) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6689634 | 0.83 | MAPK1 (0.63) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6687800 | 0.83 | LMNA (0.59) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6685305 | 0.82 | MEN1 (0.60) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6685576 | 0.80 | ALDH1A1 (0.59) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6689714 | 0.80 | ALDH1A1 (0.54) | L3MBTL1ATMALDH1A1MEN1KMT2A | |
| SCHEMBL6691516 | 0.76 | MAPK1 (0.53) | L3MBTL1ATMALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | claimed |
| WO-2004043951-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | CAREX S.A. (FR) | 2004-05-27 | — | — | WO | disclosed |