SCHEMBL6691848

SCHEMBL6691848

C=Cc1cc(CC(CC)CCCC)ccc1OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 7/20 0.40
LTA4H P09960 1/20 0.38
ALDH1A1 P00352 3/20 0.37
PPARG P37231 1/20 0.37
PPARD Q03181 1/20 0.37
PPARA Q07869 1/20 0.37
TRPV1 Q8NER1 1/20 0.37
TUBB4A P04350 1/20 0.36
TUBB P07437 1/20 0.36
TUBA3C P0DPH7 1/20 0.36
TUBA1B P68363 1/20 0.36
TUBA4A P68366 1/20 0.36
TUBB4B P68371 1/20 0.36
TUBB3 Q13509 1/20 0.36
TUBB2A Q13885 1/20 0.36
TUBB8 Q3ZCM7 1/20 0.36
TUBA3E Q6PEY2 1/20 0.36
TUBA1A Q71U36 1/20 0.36
TUBA1C Q9BQE3 1/20 0.36
TUBB6 Q9BUF5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2956197 0.80 STAT3 (0.43) LTA4HALDH1A1PPARGPPARDPPARA
SCHEMBL2229667 0.80 TDP1 (0.42) LTA4HALDH1A1TUBB1SMN1; SMN2KDM4E
SCHEMBL16134881 0.75 ALDH1A1 (0.49) ALDH1A1PPARGPPARDPPARATUBB1
SCHEMBL26831762 0.75 SIGMAR1 (0.50) SIGMAR1KDM4EALOX15ALOX12LDHA
SCHEMBL37992 0.74 TDP1 (0.45) ALDH1A1SMN1; SMN2KDM4EMEN1LMNA
SCHEMBL489052 0.74 BDKRB2 (0.39) ALDH1A1KDM4ELMNAHTTCYP3A4
SCHEMBL12856097 0.74 HTR1A (0.44) SIGMAR1LTA4HTRPV1HTR1ACYP3A4
SCHEMBL7136926 0.74 TDP1 (0.41) ALDH1A1PPARGPPARAKDM4EKMT2A
SCHEMBL153634 0.73 BDKRB2 (0.48) ALDH1A1KDM4ELMNAHTTCYP3A4
SCHEMBL9008224 0.72 LDHA (0.51) SIGMAR1KDM4EALOX15ALOX12CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004106458-A1 BLEND OF VISCOSITY MODIFIER AND LUMINESCENT COMPOUND DOW GLOBAL TECHNOLOGIES INC. (US) 2004-12-09 WO claimed