Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.62 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HNF4A | P41235 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PLAT | P00750 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | HPN | P05981 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium SCHEMBL29827094 | 0.98 | CYP2A6 (0.60) | CYP2A6HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL30146815 | 0.87 | CYP2A6 (0.64) | CYP2A6HDAC4HDAC2HDAC8HDAC6 | |
| Octane SCHEMBL2806550 | 0.86 | CYP2A6 (0.47) | CYP2A6HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL60283 | 0.83 | HDAC4 (0.65) | CYP2A6HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL30605196 | 0.83 | HDAC4 (0.65) | CYP2A6HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL380375 | 0.82 | CYP2A6 (0.50) | CYP2A6HDAC4HDAC2HDAC8HDAC6 | |
| SCHEMBL932318 | 0.81 | IDO1 (0.50) | CYP2A6ALDH1A1HPGDIDO1TSHR | |
| SCHEMBL21801283 | 0.81 | IDO1 (0.43) | CYP2A6HDAC4HDAC2HDAC8HNF4A | |
| SCHEMBL1423606 | 0.81 | IDO1 (0.51) | CYP2A6ALDH1A1HSD17B10IDO1MAPK14 | |
| SCHEMBL3805586 | 0.80 | HDAC4 (0.62) | CYP2A6HDAC4HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 282 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021054927-A2 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2021-03-25 | — | — | WO | claimed |
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2020-02-13 | — | — | US | claimed |
| WO-2018148224-A1 | PHOSPHOLIPID ETHER (PLE) CAR T CELL TUMOR TARGETING (CTCT) AGENTS | Seattle Children's Hospital (dba Seattle Children's Research Institute) (US) | 2018-08-16 | — | — | WO | claimed |
| CN-106631708-A | Preparation method of 2,6-diphenylphenol | 烟台海川化学制品有限公司 | 2017-05-10 | — | — | CN | claimed |
| US-9622969-B2 | Polymer conjugated protein micelles | SOUTH DAKOTA STATE UNIV (US) | 2017-04-18 | — | — | US | claimed |
| US-20140370110-A1 | POLYMER CONJUGATED PROTEIN MICELLES | SOUTH DAKOTA STATE UNIVERSITY (US) | 2014-12-18 | — | — | US | claimed |
| EP-1494995-B1 | 3-AMINOPHENOL DERIVATIVES SUBSTITUTED IN THE 2-POSITION, AND DYES CONTAINING THESE COMPOUNDS | PROCTER & GAMBLE (US) | 2010-09-22 | — | — | EP | claimed |
| US-7179849-B2 | Antimicrobial compositions containing colloids of oligodynamic metals | C. R. BARD, INC. (US) | 2007-02-20 | — | — | US | claimed |
| US-20050042266-A1 | Cyanoacrylate compositions containing anti-microbial agent | CLOSURE MEDICAL CORPORATION (US) | 2005-02-24 | — | — | US | claimed |
| EP-1508601-A1 | Cyanoacrylate compositions containing anti-microbial agent | Closure Medical Corporation (US) | 2005-02-23 | — | — | EP | claimed |
| US-6197321-B1 | CONTAINING MICROBIAL SANITIZER AND HARDENER | ECOLAB, INC. | 2001-03-06 | — | — | US | claimed |
| US-6066606-A | MIXTURE OF TERPENE, SURFACTANT AND WATER | RECKITT & COLMAN INC. (US) | 2000-05-23 | — | — | US | claimed |
| US-5312624-A | Sanitizing drains by dispensing chemicals in housings | ECOLAB INC. (US) | 1994-05-17 | — | — | US | claimed |
| US-4669491-A | Compositions and process for applying protective covering and extensions to fingernails | Weisberg, Renee (US) | 1987-06-02 | — | — | US | claimed |
| US-4468508-A | Glycidyl ether of novolak type substituted phenolic resin, process for producing the same, and encapsulating compound composed mainly of the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-08-28 | — | — | US | claimed |
| EP-0046270-A1 | Novel derivatives of bio-affecting phenolic compounds and pharmaceutical composition containing them | INTERx RESEARCH CORPORATION (US) | 1982-02-24 | — | — | EP | claimed |
| WO-1980000791-A1 | B-GLUCURONIDASE ACTIVITY AND/OR PH-DEPENDENT PHARMACEUTICALS AND THEIR METHODS OF PRODUCTION AND USE FOR SELECTIVE TREATMENT OF DISEASES | SCHWIMMER A (US) | 1980-05-01 | — | — | WO | claimed |
| US-4157977-A | HYDROXYACETIC ACID, PHENOLIC DERIVATIVE, ANIONIC SURFACTANT | CHEMED CORPORATION (US) | 1979-06-12 | — | — | US | claimed |
| US-RE28778-E | ANIONIC SURFACTANT | WEST LABORATORIES, INC. (US) | 1976-04-20 | — | — | US | claimed |
| US-3947468-A | Production of dibenzopyrans, their isomeric fluorenols and dibenzothiopyrans | GENERAL ELECTRIC COMPANY (US) | 1976-03-30 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | GSTK1, GSTO1, GSTM2 | CYP2A6 1261/4885HDAC4 2230/4885HDAC2 1604/4885 |
| US-20140370110-A1 | POLYMER CONJUGATED PROTEIN MICELLES | MTDH, PSMG3, GHITM | CYP2A6 4254/4885HDAC4 2934/4885HDAC2 4388/4885 |
| US-20050042266-A1 | Cyanoacrylate compositions containing anti-microbial agent | CLSPN, PCNA, CDC73 | CYP2A6 4014/4885HDAC4 1686/4885HDAC2 3520/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.