Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA9 | Q16790 | 4/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | GPR183 | P32249 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 6/20 | 0.39 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6697103 | 0.92 | PARP1 (0.43) | PARP1 | |
| SCHEMBL6692009 | 0.87 | CA12 (0.46) | CA2CA9CA12CA1PLA2G2A | |
| SCHEMBL6692578 | 0.83 | LMNA (0.47) | HTR4ACHEPARP1 | |
| SCHEMBL15688203 | 0.82 | HRH4 (0.43) | GPR183 | |
| SCHEMBL6692234 | 0.81 | HTR4 (0.52) | HTR4ACHE | |
| SCHEMBL6697097 | 0.79 | PARP1 (0.42) | PARP1 | |
| SCHEMBL6688415 | 0.79 | CNR2 (0.48) | CA2CA9CA12CA1CHRM3 | |
| SCHEMBL6692750 | 0.79 | CNR2 (0.48) | CA2CA9CA12CA1CHRM3 | |
| SCHEMBL23981505 | 0.77 | POLB (0.42) | HTR4PARP1 | |
| SCHEMBL30396921 | 0.77 | POLB (0.42) | HTR4PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |